Emerging Infectious Disease Network
Transmissible
Spongiform Encephalopathies (TSE)
The
Transmissible Spongiform Encephalopathies Reference Library is a
collaborative initiative of international veterinary, medical and
scientific experts to share information and enhance academic discussion
of emerging infectious diseases and issues associated with
preparedness, response, mitigation and policy. ..
Contact:
Stephen
M. Apatow
Founder,
Director of Research & Development
Humanitarian
Resource Institute (UN:NGO:DESA)
Humanitarian University
Consortium Graduate Studies
Center
for Medicine, Veterinary Medicine & Law
Phone:
203-668-0282
Email:
s.m.apatow@humanitarian.net
Internet:
www.humanitarian.net
Pathobiologics
International
Internet:
www.pathobiologics.org.....
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In the
Spotlight
- Research indicates mad cow pathogen can cause both
sporadic or classical Creutzfeldt-Jacob disease (CJD) and varient form:
May 7
(HRI) - Call for International Action by the World Organization for
Animal
Health (OIE), Food and Agriculture Organization of the United Nations
(FAO)
and World Health Organization (WHO).
- Transmissible Spongiform Encephalopathies (BSE) in
North
America: Humanitarian Resource Institute.
- Risk
Analysis of prion disease in animals: C.I. Lasmézas
& D.B. Adams (eds), OIE, Scientific and Technical Review, Volume 22
(1), April 2003.
- Advancing Prion Science: Guidance for the National
Prion
Research Program (2003): National Academy of Sciences
- EU Geographical BSE Risk Assessment: Country
Reports, Outcome of discussions: Opinions - Minutes.
- Genome Affects Human Forms of “Mad Cow” Disease:
Genome News Network (GNN), 23 January 2004.
- Agent Summary Statements, Section VII-D: Prions,
CDC: Office of Health and Safety (OHS), BMBL Section VII.
The GNN article speculates that the chance of
developing a human prion disease in any form is less than one in a
million. This statistic is being challenged by research at Yale
University (Medline) that found 13 percent of Alzheimer's
patients actually had CJD and potential association with BSE prion
propagation as
either variant CJD-like or sporadic CJD-like prion strains (demonstrated in transgenic mice expressing human prion
protein).
For additional information on genomics research, visit the HRI Bioinformatics: Pathological Diagnostics web
site.
Food
& Agriculture Organization of the United Nations
- Bovine
Spongiform Encephalopathy (Mad Cow Disease): FAO recommends precautions
FAO estimates that between 1986-96 up to today, meat and bone meal
(MBM) from Europe was exported to more than 100 countries.
Around 100 countries imported live cattle. Some countries also
re-exported MBM to third countries. All countries which have
imported cattle or meat and bone meal that originated from Western
Europe, during and since the 1980s, can be therefore considered at risk
from the disease. Regions that have imported sizeable quantities of
meat meal from the UK during and since the 1980s include the Near East,
Eastern Europe and Asia.
TSE
Educational Resources:
General
Veterinary Research & Publications
General Information: Emerging Infectious Diseases
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